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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFKP
All Species:
6.06
Human Site:
T493
Identified Species:
11.11
UniProt:
Q01813
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01813
NP_002618.1
784
85596
T493
K
Y
L
E
E
I
A
T
Q
M
R
T
H
S
I
Chimpanzee
Pan troglodytes
XP_507625
746
81795
T455
K
Y
L
E
E
I
A
T
Q
M
R
T
H
S
I
Rhesus Macaque
Macaca mulatta
XP_001118490
717
78539
L451
A
Y
L
G
L
L
E
L
S
A
A
R
E
K
H
Dog
Lupus familis
XP_535201
901
98160
Q604
K
F
L
E
D
I
A
Q
Q
M
R
T
H
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUA3
784
85437
E492
K
Y
L
E
K
I
A
E
Q
M
H
S
H
S
I
Rat
Rattus norvegicus
P47860
788
85702
E493
K
Y
L
E
K
I
A
E
Q
M
H
S
K
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511162
864
94802
E564
K
Y
L
E
Q
I
A
E
Q
M
R
T
H
N
I
Chicken
Gallus gallus
NP_989554
769
83907
A470
K
Y
F
E
E
I
S
A
T
I
S
T
F
G
I
Frog
Xenopus laevis
NP_001091319
786
86623
E485
K
Y
F
D
Q
I
A
E
Q
L
R
T
H
K
I
Zebra Danio
Brachydanio rerio
XP_002666643
787
86261
E486
K
H
I
D
K
I
A
E
Q
M
R
K
Y
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52034
788
86630
A492
G
K
F
K
E
I
A
A
R
L
K
E
F
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27483
756
83282
E485
S
E
M
D
L
I
A
E
G
L
N
S
N
N
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16862
959
104599
Y671
A
D
L
G
M
I
A
Y
Y
F
Q
K
Y
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
89.4
78.9
N.A.
88.5
87.9
N.A.
77.1
70.7
81.3
79.6
N.A.
58.8
N.A.
40.6
N.A.
Protein Similarity:
100
95
90.4
83.5
N.A.
93.6
93.4
N.A.
84.1
82
90.5
89.3
N.A.
75.8
N.A.
59.6
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
73.3
60
N.A.
80
46.6
60
46.6
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
80
N.A.
93.3
60
80
86.6
N.A.
53.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
85
16
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
24
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
54
31
0
8
47
0
0
0
8
8
8
0
% E
% Phe:
0
8
24
0
0
0
0
0
0
8
0
0
16
0
8
% F
% Gly:
8
0
0
16
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
16
0
47
0
8
% H
% Ile:
0
0
8
0
0
93
0
0
0
8
0
0
0
0
77
% I
% Lys:
70
8
0
8
24
0
0
0
0
0
8
16
8
24
0
% K
% Leu:
0
0
62
0
16
8
0
8
0
24
0
0
0
0
0
% L
% Met:
0
0
8
0
8
0
0
0
0
54
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
8
31
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
8
62
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
47
8
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
8
0
8
24
0
31
0
% S
% Thr:
0
0
0
0
0
0
0
16
8
0
0
47
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
62
0
0
0
0
0
8
8
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _